Hereditary diseases of the cat
Breed specific hereditary diseases
You breed or think about breeding pedigree cats seriously or you are owner of a fancier pedigree cat whose origin is not quite clear for various reasons?
Below we list some of the best known pedigreed cats and their specific hereditary diseases and testing options. The individual names of the hereditary diseases are not discussed, since there is already enough information material on the net.
British Shorthair, -Longhair / Persian / Chartreux / Exotic / Selkirk Rex
Hereditary diseases:
HCM (Hypertrophic Cardiomyopathy), PKD (Polycystic Kidney Disease)
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Genetic inheritance tests are not meaningful, as they are intended for other breeds.
PKD: Sonic or hereditary test for the PKD1 gene. The sound is only meaningful from the 1st year of life – before that, however, in the case of an affected disease, it is already possible.
PKD1 gene is present in Persians as well as their outcrosses.
Maine Coon
Hereditary diseases:
HCM (hypertrophic cardiomyopathy), hip dysplasia, PK (pyruvate kinase deficiency), SMA (spinal muscular atrophy).
Investigation options:
HCM: Sound & Inheritance Test. In breeding before the first breeding use.
Repeat sonication approximately every 1-2 years until 6/7 years of age. Year of life.
Genetic inheritance tests for Maine Coon available – but are not 100% conclusive.
Hip dysplasia: radiographs of the hip
PK: Genetic test
SMA: genetic test
Norwegian Forest Cat
Hereditary diseases:
Glycogen storage disease type IV, HCM (hypertrophic cardiomyopathy), PK (pyruvate kinase deficiency).
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Genetic inheritance tests are not meaningful, as they are intended for other breeds.
PK: Genetic test
Glycogen storage disease type IV: genetic test
Ragdoll
Hereditary diseases:
HCM (hypertrophic cardiomyopathy), MPS VI (mucopolysaccharidosis type VI), PKD (polycystic kidney disease)
Investigation options:
HCM: Sound & Inheritance Test. In breeding before the first breeding use.
Repeat sonication approximately every 1-2 years until 6/7 years of age. Year of life.
Inheritance test not 100% meaningful.
MPS VI: Genetic test
PKD: Sonic or hereditary test for the PKD1 gene. The sound is only meaningful from the 1st year of life – before that, however, in the case of an affected disease, it is already possible.
Russian blue
Hereditary diseases:
PKD (Polycystic Kidney Disease)
Investigation options:
PKD: Sound
Siberian Forest Cat
Hereditary diseases:
HCM (Hypertrophic Cardiomyopathy), PKD (Polycystic Kidney Disease), PK (Pyruvate Kinase Deficiency)
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Genetic inheritance tests are not meaningful, as they are intended for other breeds.
PKD: Sound. In breeding before the first breeding use.
PK: Genetic test
Holy Burma
Hereditary diseases:
MPS VI (Mucopolysaccharidosis type VI), PKD (Polycystic Kidney Disease)
Investigation options:
PKD: Sound. In breeding before the first breeding use.
MPS VI: Genetic test
Bengal
Hereditary diseases:
HCM (hypertrophic cardiomyopathy), hip dysplasia, rdAc-PRA (progressive retinal atrophy), PK (pyruvate kinase deficiency), PKD (polycystic kidney disease).
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Hip dysplasia: radiographs of the hip
rdAc-PRA: genetic test
PK: Genetic test
PKD: Sound. In breeding before the first breeding use.
Hereditary diseases of the cat
Breed specific hereditary diseases
You breed or think about breeding pedigree cats seriously or you are owner of a fancier pedigree cat whose origin is not quite clear for various reasons?
Below we list some of the best known pedigreed cats and their specific hereditary diseases and testing options. The individual names of the hereditary diseases are not discussed, since there is already enough information material on the net.
British Shorthair, -Longhair / Persian / Chartreux / Exotic / Selkirk Rex
Hereditary diseases:
HCM (Hypertrophic Cardiomyopathy), PKD (Polycystic Kidney Disease)
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Genetic inheritance tests are not meaningful, as they are intended for other breeds.
PKD: Sonic or hereditary test for the PKD1 gene. The sound is only meaningful from the 1st year of life – before that, however, in the case of an affected disease, it is already possible.
PKD1 gene is present in Persians as well as their outcrosses.
Maine Coon
Hereditary diseases:
HCM (hypertrophic cardiomyopathy), hip dysplasia, PK (pyruvate kinase deficiency), SMA (spinal muscular atrophy).
Investigation options:
HCM: Sound & Inheritance Test. In breeding before the first breeding use.
Repeat sonication approximately every 1-2 years until 6/7 years of age. Year of life.
Genetic inheritance tests for Maine Coon available – but are not 100% conclusive.
Hip dysplasia: radiographs of the hip
PK: Genetic test
SMA: genetic test
Norwegian Forest Cat
Hereditary diseases:
Glycogen storage disease type IV, HCM (hypertrophic cardiomyopathy), PK (pyruvate kinase deficiency).
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Genetic inheritance tests are not meaningful, as they are intended for other breeds.
PK: Genetic test
Glycogen storage disease type IV: genetic test
Ragdoll
Hereditary diseases:
HCM (hypertrophic cardiomyopathy), MPS VI (mucopolysaccharidosis type VI), PKD (polycystic kidney disease)
Investigation options:
HCM: Sound & Inheritance Test. In breeding before the first breeding use.
Repeat sonication approximately every 1-2 years until 6/7 years of age. Year of life.
Inheritance test not 100% meaningful.
MPS VI: Genetic test
PKD: Sonic or hereditary test for the PKD1 gene. The sound is only meaningful from the 1st year of life – before that, however, in the case of an affected disease, it is already possible.
Russian blue
Hereditary diseases:
PKD (Polycystic Kidney Disease)
Investigation options:
PKD: Sound
Siberian Forest Cat
Hereditary diseases:
HCM (Hypertrophic Cardiomyopathy), PKD (Polycystic Kidney Disease), PK (Pyruvate Kinase Deficiency)
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Genetic inheritance tests are not meaningful, as they are intended for other breeds.
PKD: Sound. In breeding before the first breeding use.
PK: Genetic test
Holy Burma
Hereditary diseases:
MPS VI (Mucopolysaccharidosis type VI), PKD (Polycystic Kidney Disease)
Investigation options:
PKD: Sound. In breeding before the first breeding use.
MPS VI: Genetic test
Bengal
Hereditary diseases:
HCM (hypertrophic cardiomyopathy), hip dysplasia, rdAc-PRA (progressive retinal atrophy), PK (pyruvate kinase deficiency), PKD (polycystic kidney disease).
Investigation options:
HCM: Sound. In breeding before the first breeding use.
Repetition approx. every 1-2 years until the 6th/7th year. Year of life.
Hip dysplasia: radiographs of the hip
rdAc-PRA: genetic test
PK: Genetic test
PKD: Sound. In breeding before the first breeding use.
